Kriuchkova N A
Zh Vyssh Nerv Deiat Im I P Pavlova. 1978 Nov-Dec;28(6):1280-7.
Functional maturation of perforant pathway synapses on neurones of the dorsal hippocampus and fascia dentata was examined in unanaesthetized rabbits 1 to 25 days of age, by means of extracellular recording of fiold potentials and of neuronal responses to electrical stimulation of the cortical afferent input. In the areas CA1 and CA3 of the dorsal hippocampus, field potentials, activating and inhibitory neuronal responses to stimulation of the perforant pathway with single impulses were recorded from the first day of the postnatal life, while short-latency responses of the fascia dentata were revealed later--at the end of the first week or the beginning of the second week of life. The data obtained suggest that in rabbits, the synapses of the perforant pathway are functioning from the first days after birth. The postnatal development of the cortical afferent input to the hippocampus is related to the maturation of the dentate gyrus.
通过细胞外记录场电位以及神经元对皮质传入输入电刺激的反应，在1至25日龄的未麻醉家兔中检查了背侧海马体和齿状回神经元上穿通通路突触的功能成熟情况。在背侧海马体的CA1和CA3区域，从出生后第一天开始记录场电位、对穿通通路单脉冲刺激的激活和抑制性神经元反应，而齿状回的短潜伏期反应则在出生后第一周结束或第二周开始时才显现出来。所获得的数据表明，在家兔中，穿通通路的突触从出生后的第一天就开始发挥作用。海马体皮质传入输入的出生后发育与齿状回的成熟有关。
