[氨甲蝶呤对兔阑尾淋巴组织的免疫抑制作用及影响]
[Immunosuppressive action and effects of amethopterin on the lymphoid tissue of the rabbit appendix].
作者信息
Laurentaci G, Catalano G, Chiumarulo C, Di Rienzo G, Palasciano N
出版信息
Minerva Med. 1980 Jan 21;71(2):103-10.
PMID:7354928
Abstract
Effects of amethopterin (MTX) on lymphoid tissue of rabbit appendix have been evaluated. The drug caused an evident depletion of lymphoid cells. This finding suggested the relevance of cytotoxicity in the mechanism of immune suppression. Discontinuation of drug treatment demonstrated a tendency toward the reorganization of the lymphoid tissue.
摘要
已评估了氨甲蝶呤（MTX）对兔阑尾淋巴组织的影响。该药物导致淋巴细胞明显减少。这一发现表明细胞毒性在免疫抑制机制中具有相关性。停止药物治疗显示出淋巴组织有重新组织的趋势。
Zotero 插件