Kerkering K W, Robertson L W, Kodroff M B, Mueller D G, Kirkpatrick B V
Pediatrics. 1980 Feb;65(2):326-30.
A case of cardiomegaly with unilateral pulmonary edema is presented. The predisposing etiologies were severe hypoglycemia and a hypertonic glucose infusion into a branch of the left lower lobe pulmonary vein. Resolution resulted following maintenance of adequate glucose levels, vigorous cardiopulmonary support, and repositioning of the catheter tip in the inferior vena cava. The pathophysiologic mechanism was direct endothelial injury with an osmotic diuresis. The role of the release of a vasoactive substance was postulated.
本文报告一例伴有单侧肺水肿的心脏扩大病例。诱发病因是严重低血糖以及将高渗葡萄糖输注至左下肺静脉的一个分支。在维持适当血糖水平、积极进行心肺支持以及将导管尖端重新放置在下腔静脉后,症状得到缓解。病理生理机制是伴有渗透性利尿的直接内皮损伤。推测了血管活性物质释放的作用。