Morens D M, Anderson L J, Hurwitz E S
Pediatrics. 1980 Jan;65(1):21-5.
Information about 261 cases of Kawasaki disease (KD) was reported to the Center for Disease Control (CDC) between July 1976 and July 1978. KD occurred at all times of the year in young, previously healthy children throughout the United States. KD was more common in infants and toddlers, males, and Asian and part-Asian children. The illness was characterized by acute onset of prolonged high fever; maculopapular or scarlatiniform rash; adenopathy; injection of the conjunctival and mucous membranes of the upper respiratory tract; redness of the palms and soles; indurative edema of the extremities; desquamation, arthralgias; and elevated white blood cell count, erythrocyte sedimentation rate, and platelet count. Complications included gallbladder disease and carditis; 2.8% died. Surviving patients were hospitalized for a mean of 8.9 days.
1976年7月至1978年7月期间，261例川崎病（KD）病例信息被报告至疾病控制中心（CDC）。在美国各地，此前健康的幼儿全年任何时候都可能发生川崎病。川崎病在婴儿、学步儿童、男性以及亚洲和部分亚裔儿童中更为常见。该病的特征为急性起病，持续高热；斑丘疹或猩红热样皮疹；淋巴结病；上呼吸道结膜和粘膜充血；手掌和脚底发红；四肢硬结性水肿；脱皮、关节痛；白细胞计数、红细胞沉降率和血小板计数升高。并发症包括胆囊疾病和心脏炎；2.8%的患者死亡。存活患者的平均住院时间为8.9天。
