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蒙古的川崎病:1996-2008 年两项全国性回顾性调查结果。

Kawasaki disease in Mongolia: results from 2 nationwide retrospective surveys, 1996-2008.

机构信息

Department of Epidemiology and Biostatistics, School of Public Health, Health Sciences University of Mongolia, Mongolia.

出版信息

J Epidemiol. 2011;21(4):293-8. doi: 10.2188/jea.je20100144. Epub 2011 Jun 18.

DOI:10.2188/jea.je20100144
PMID:21691035
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3899422/
Abstract

BACKGROUND

Kawasaki disease (KD) has been reported in many countries. However, the incidence of KD in Mongolia is not known. This is the first report of incident cases of KD in Mongolia, which were identified using data from 2 nationwide surveys.

METHODS

Two nationwide retrospective surveys were conducted: medical histories were collected from patients aged 0 to 16 years who were hospitalized countrywide between 1996 and 2008. Hospital records for these patients were also reviewed. Nationwide training seminars on KD were conducted before each survey.

RESULTS

For the nationwide surveys, the participation rates among all hospitals with pediatric wards were 97% and 94%. Inpatient medical histories from 1996 through 2008 were reviewed, and, among children younger than 16 years, 9 patients with KD were investigated. The age of KD patients ranged from 1.4 to 14 years; 7 of 9 patients were male. Six (67%) patients fulfilled all 6 clinical diagnostic criteria; the other 3 (33%) were defined as having KD based on the presence of 5 such criteria. Fever persisting 5 or more days, bilateral conjunctival congestion, and changes of the lips and oral cavity were the most common symptoms, and cervical lymphadenopathy was the least common symptom. Cardiac sequelae developed in 5 of the patients, 4 of whom were older than 10 years.

CONCLUSIONS

The results of these nationwide surveys reveal that KD cases do exist in Mongolia. However, knowledge of KD among Mongolian pediatricians is likely to be poor. Thus, there is a need to augment their understanding to improve management of KD patients. Further studies are crucial to clarify the epidemiologic characteristics of KD in Mongolia.

摘要

背景

川崎病(KD)已在许多国家报道过。然而,蒙古的 KD 发病率尚不清楚。这是蒙古首次报告 KD 发病情况,通过对全国 2 次调查的数据识别出 KD 发病情况。

方法

进行了全国范围的 2 次回顾性调查:收集了 1996 年至 2008 年期间全国住院的年龄在 0 至 16 岁的患者的病史,同时还回顾了这些患者的住院记录。在每次调查前都举办了关于 KD 的全国性培训研讨会。

结果

在全国性调查中,有儿科病房的所有医院的参与率分别为 97%和 94%。对 1996 年至 2008 年的住院病历进行了回顾,在 16 岁以下的儿童中,调查了 9 例 KD 患者。KD 患者的年龄范围为 1.4 至 14 岁;9 例患者中 7 例是男性。6 例(67%)患者符合全部 6 项临床诊断标准;另外 3 例(33%)则根据 5 项标准被定义为 KD。最常见的症状为发热持续 5 天或以上、双侧结膜充血、唇舌改变,而最不常见的症状为颈部淋巴结肿大。5 例患者出现了心脏后遗症,其中 4 例患者年龄大于 10 岁。

结论

这些全国性调查的结果表明,KD 病例确实存在于蒙古。然而,蒙古儿科医生对 KD 的了解可能较差。因此,需要提高他们的认识,以改善 KD 患者的管理。进一步的研究对于阐明蒙古 KD 的流行病学特征至关重要。