Leichner P K, Rosenshein N B, Leibel S A, Order S E
Radiology. 1980 Mar;134(3):729-34. doi: 10.1148/radiology.134.3.7355227.
Radiophosphorus (32P) has become the preferred radioisotope for intraperitoneal radiotherapy in the adjuvant treatment of ovarian cancer. In a study of the distribution and tissue dose of intraperitoneally administered 32P in rabbits, effective half-lives of 32P and the radiation dose absorbed by intra-abdominal tissues were determined. Results show that 32P is not uniformly distributed over the peritoneal surfaces and that many areas are minimally irradiated. It is concluded that a significant fraction of the 32P distribution is systemic and that the beta-ray dose for intra-abdominal tissues is much lower than suggested by theoretical models.
