Sullivan D C, Harris C C, Currie J L, Wilkinson R H, Creasman W T
Radiology. 1983 Feb;146(2):539-41. doi: 10.1148/radiology.146.2.6849103.
Seven patients received intraperitoneal chromic phosphate (32P) suspension in a 3-ml bolus with a saline flush, and another ten patients were given the suspension in a 500-ml infusion of normal saline. During the first six hours after administration, most 32P activity redistributed to the gravity-dependent portion of the peritoneal cavity. From 24 hours up to seven weeks after administration, activity distributions were fixed. Dispersions were heterogeneous in every patient, but the most marked examples of localized activity occurred in patients who had received bolus injections. We concluded that large-volume infusions and frequent changes in patient position for several hours following the infusion, contribute to improved dispersion of 32P suspension.
7名患者接受了3毫升大剂量腹腔内注射含生理盐水冲洗的磷酸铬（32P）混悬液，另外10名患者接受了在500毫升生理盐水中输注该混悬液的治疗。给药后的前6小时内，大部分32P活性重新分布至腹腔的重力依赖部分。给药后24小时直至7周，活性分布固定。每位患者的分布均不均匀，但局部活性最显著的例子发生在接受大剂量注射的患者中。我们得出结论，大容量输注以及输注后数小时内频繁改变患者体位，有助于改善32P混悬液的分散。
