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[对前列腺癌患者雌激素诱导的男性乳腺增生进行乳腺腺体照射作为预防性治疗(作者译)]

[Irradiation of the breast glands as prophylactic treatment of an estrogen-induced gynecomastia in patients with prostate carcinomas (author's transl)].

作者信息

Metzger H, Junker A, Voss A C

出版信息

Strahlentherapie. 1980 Feb;156(2):102-4.

PMID:7355408
Abstract

One hundred and four patients with histologically demonstrated prostate carcinomas were submitted to a bilateral orchiectomy. Before the beginning of a hormone therapy, both breast glands were irradiated prophylactically. The patients were observed between two and thirty months. The radiotherapy was executed with electrons with an energy of 10 to 12 MeV and by a stationary field which had a size of 10 X 10 cm. A total surface dose of 12,0 Gy was applicated in four single doses of 3,0 Gy each. The symptom-less healing of 45% of the pateints and the rate of only 29% of patients with gynecomastia is considered to be a good result. In view of the success achieved by the hormone therapy, subjective complaints such as hyperesthesia, pains and pruritus are regarded to be less important.

摘要

104例经组织学证实为前列腺癌的患者接受了双侧睾丸切除术。在开始激素治疗前,对双侧乳腺进行了预防性照射。对患者进行了2至30个月的观察。放疗采用能量为10至12兆电子伏的电子线,通过一个大小为10×10厘米的固定野进行。总表面剂量为12.0戈瑞,分4次给予,每次3.0戈瑞。45%的患者无症状愈合,男性乳房发育患者的发生率仅为29%,这被认为是一个良好的结果。鉴于激素治疗取得的成功,诸如感觉过敏、疼痛和瘙痒等主观症状被认为不太重要。

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