Brown K H, Rajan M M, Chakraborty J, Aziz K M
Am J Clin Nutr. 1980 Feb;33(2):212-7. doi: 10.1093/ajcn/33.2.212.
Field studies to determine the effects of a large dose of water miscible vitamin A on selected parameters of children's immunological function were completed in rural Bangladesh. There was no difference between vitamin A treated or control groups in tetanus antitoxin responses after tetanus toxoid immunization or in skin test reactivity to common antigens. Subsequent studies with mice demonstrated vitamin A dose-related antitoxin responses, but the animals required amounts of vitamin that would be likely cause undesirable side effects if administered in similar doses to children.
在孟加拉国农村地区完成了实地研究，以确定大剂量水溶性维生素A对儿童免疫功能选定参数的影响。在破伤风类毒素免疫后，维生素A治疗组和对照组在破伤风抗毒素反应或对常见抗原的皮肤试验反应性方面没有差异。随后对小鼠的研究表明维生素A的抗毒素反应与剂量相关，但如果给儿童施用类似剂量的维生素，动物所需的维生素量可能会导致不良副作用。
