Friess A E, Sinowatz F, Skolek-Winnisch R, Träautner W
Anat Embryol (Berl). 1980;158(2):179-91. doi: 10.1007/BF00315905.
The finestructural changes of the interareolar porcine placenta during pregnancy are described. After perfusion fixation of the placenta the change in the thickness of the placental barrier from day 30 to day 110 of gestation is much more evident than after immerson fixation as has been used by all former authors. The alterations are due to the indentation of both the trophoblast and uterine epithelium by their corresponding capillary-network. This indentation is limited to the lateral wall and the summit of the chorionic ridges, while at the base the trophoblast as well as the uterine epithelium remains high columnar. This indicates that in the interareolar porcine placenta, which is represented by the chorionic ridges and the corresponding endometrial folds, at least two different areas with different structure and function may be discerned. 1) The lateral side and the top of the chorionic ridges seem to be predestinated for gaseous exchange. The placental barrier in this area is often less than 2 micrometers. 2) The transport of blood-borne nutrients takes place at the base of the chorionic ridges. This transport seems to be facilitated by an intercellular channel system between the uterine epithelial cells.
本文描述了妊娠期间猪乳晕间胎盘的超微结构变化。胎盘经灌注固定后，妊娠第30天至第110天胎盘屏障厚度的变化比以往所有作者使用的浸入固定法更为明显。这些变化是由于滋养层和子宫上皮被其相应的毛细血管网压陷所致。这种压陷仅限于绒毛嵴的侧壁和顶部，而在底部，滋养层和子宫上皮仍为高柱状。这表明，在以绒毛嵴和相应子宫内膜皱襞为代表的猪乳晕间胎盘，至少可以识别出两个具有不同结构和功能的不同区域。1） 绒毛嵴的外侧和顶部似乎是进行气体交换的预定部位。该区域的胎盘屏障通常小于2微米。2） 血源性营养物质的运输发生在绒毛嵴的底部。这种运输似乎是由子宫上皮细胞之间的细胞间通道系统促进的。
