De Fazio G, Caner J, Vicente M
Arch Virol. 1980;63(3-4):305-9. doi: 10.1007/BF01315037.
Virazole (1, beta-D-ribofuranosyl-1,2,4-triazole-3-carboxamide = Ribavirin), a synthetic nucleoside analogue, has been successfully used against tomato spotted wilt virus (TSWV) in tomato and tobacco plants. In tomato, the most efficient concentration to control TSWW was 500 mg/l while in tobacco, concentrations of 100 mg/l were sufficient to control systemic infection. When the plants did not show a systemic reaction virus could not be recovered from inoculated and treated tomato and tobacco plants by means of the local lesion assay. The results point out the response of a new plant virus to Virazole and indicate a possibility of controlling TSWW systemic infection.
病毒唑（1-β-D-呋喃核糖基-1,2,4-三唑-3-甲酰胺=利巴韦林），一种合成核苷类似物，已成功用于防治番茄和烟草植株中的番茄斑萎病毒（TSWV）。在番茄中，控制TSWV的最有效浓度为500毫克/升，而在烟草中，100毫克/升的浓度就足以控制系统感染。当植株未表现出系统反应时，通过局部病斑测定法无法从接种和处理过的番茄和烟草植株中分离出病毒。这些结果指出了一种新型植物病毒对病毒唑的反应，并表明了控制TSWV系统感染的可能性。
