Raicht R F, Cohen B I, Fazzini E P, Sarwal A N, Takahashi M
Cancer Res. 1980 Feb;40(2):403-5.
Diets rich in vegetables are associated with a low incidence of colon cancer. Since plant sterols are plentiful in vegetarian diets, we studied the effect of beta-sitosterol on colon tumor formation in rats treated with the carcinogen N-methyl-N-nitrosourea. We demonstrated that beta-sitosterol nullified in part the effect of this direct-acting carcinogen on the colon. We suggest that plant sterols may have a protective dietary action action to retard colon tumor formation. The beneficial effects of vegetarian diets may be enhanced because of the presence of these compounds.
富含蔬菜的饮食与结肠癌的低发病率相关。由于植物甾醇在素食中含量丰富，我们研究了β-谷甾醇对用致癌物N-甲基-N-亚硝基脲处理的大鼠结肠肿瘤形成的影响。我们证明，β-谷甾醇部分抵消了这种直接作用致癌物对结肠的影响。我们认为植物甾醇可能具有延缓结肠肿瘤形成的保护性饮食作用。由于这些化合物的存在，素食的有益效果可能会增强。
