Mitz M, Prakash A S, Melvin J, Piering W
Arch Phys Med Rehabil. 1980 Jan;61(1):45-8.
Eighty-four patients with primary end stage renal disease (ESRD) of varying duration and severity were investigated by a single determination of facial nerve latency and determination of motor nerve conduction velocities of the peroneal, median, and ulnar nerves. Electrophysiologic evidence of motor neuropathy was found in 72 patients. In the facial nerve, conduction was abnormal in 82% of the patients; in the peroneal nerve it was abnormal in 68%; in the median nerve it was abnormal in 36%; and in the ulnar nerve it was abnormal in 22%. The facial nerve was the most sensitive indicator of uremic neuropathy of the 4 motor nerves studied. Information obtained from monitoring the facial nerve in patients with chronic renal failure will add significantly to the data used to identify uremic neuropathy. Combined studies of the facial, peroneal, and median nerves should identify most patients with uremic neuropathy.
对84例病程和严重程度各异的原发性终末期肾病（ESRD）患者进行了一项研究，单次测定面神经潜伏期，并测定腓总神经、正中神经和尺神经的运动神经传导速度。72例患者发现有运动神经病变的电生理证据。面神经方面，82%的患者传导异常；腓总神经方面，68%的患者传导异常；正中神经方面，36%的患者传导异常；尺神经方面，22%的患者传导异常。在所研究的4条运动神经中，面神经是尿毒症性神经病变最敏感的指标。从监测慢性肾衰竭患者面神经获得的信息将显著增加用于识别尿毒症性神经病变的数据。对面神经、腓总神经和正中神经进行联合研究应能识别出大多数尿毒症性神经病变患者。
