Huston C C, Bivins B A, Ernst C B, Griffen W O
Arch Surg. 1980 Feb;115(2):165-7. doi: 10.1001/archsurg.1980.01380020033008.
In a retrospective review of 100 consecutive patients requiring above-knee amputation for arterial occlusive disease, the operative mortality was 15%. An additional 26% mortality occurred during a two-year follow-up period. Principal causes of death were sepsis in 54%, heart disease in 16%, and stroke in 11%. The poor prognosis of patients requiring amputation was related to progression of systemic diseases and to generalized debility among these patients.
