Donnerberg R L, Druzgalski C K, Hamlin R L, Davis G L, Campbell R M, Rice D A
Br J Dis Chest. 1980 Jan;74(1):23-31.
Alterations of sound transfer function of the lung in pre-congested and congested states were studied in a canine model as an index of the accumulation of lung liquids. Pulmonary congestion was produced by graduated inflations of a balloon in the left atrium. Different degrees of pulmonary congestion were documented by post-mortem wet to dry lung weight ratios. Sound transfer function of the lung was determined utilizing passive sound transmission in the audio freqency range consisting of sinusoidal oscillations swept from 50 Hz to 2 kHz. Sound transfer function in dB was defined as 20 times the logarithm of sound output divided by sound input. These functions were computed for pre-congested and congested states of the lung and the differential values correlated with the post-mortem wet to dry weight ratios of the lung. The magnitude of sound transfer function of the lung correlated well with increasing accumulation of intravascular and extravascular lung liquids and provided a quantitative index of pulmonary congestion.
在犬类模型中研究了肺在充血前期和充血状态下声音传递功能的改变，以此作为肺内液体蓄积的指标。通过向左心房内逐步充气使气球膨胀来造成肺充血。通过死后肺湿重与干重之比记录不同程度的肺充血。利用音频频率范围内的被动声音传输来测定肺的声音传递功能，该频率范围由从50赫兹扫频至2千赫兹的正弦振荡组成。以分贝为单位的声音传递功能定义为声音输出除以声音输入的对数的20倍。计算肺在充血前期和充血状态下的这些功能，并将差值与肺的死后湿重与干重之比相关联。肺声音传递功能的大小与血管内和血管外肺液体的蓄积增加密切相关，并提供了肺充血的定量指标。
