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因视觉剥夺导致的弱视中的对比敏感度

Contrast sensitivity in amblyopia due to stimulus deprivation.

作者信息

Levi D M, Harwerth R S

出版信息

Br J Ophthalmol. 1980 Jan;64(1):15-20. doi: 10.1136/bjo.64.1.15.

Abstract

Contrast sensitivity functions for sinusoidal gratings of varying spatial frequency and stimulus duration were determined for both eyes of 2 patients with amblyopia due to early occlusion and lid closure. The amblyopic eyes showed reduced contrast sensitivity over a wide range of spatial frequencies and stimulus durations, and the temporal integration time of the amblyopic eye was increased by comparison with the non-amblyopic eye at high spatial frequencies. When the gratings were flickered at 10 Hz the sensitivity for both flicker and pattern detection was reduced in the amblyopic eye over the entire spatial frequency range. Abnormal flicker perception by the amblyopic eyes was also evident in the reduced photopic luminosity functions of these patients.

摘要

对2例因早期遮盖和眼睑闭合导致弱视的患者双眼,测定了不同空间频率和刺激持续时间的正弦光栅的对比敏感度函数。弱视眼在广泛的空间频率和刺激持续时间范围内对比敏感度降低,在高空间频率下,与非弱视眼相比,弱视眼的时间整合时间增加。当光栅以10Hz闪烁时,弱视眼在整个空间频率范围内对闪烁和图案检测的敏感度均降低。这些患者的明视觉光度函数降低也表明弱视眼存在异常的闪烁感知。

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本文引用的文献

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Spatiotemporal modulation transfer in the human eye.人眼的时空调制传递
J Opt Soc Am. 1967 Sep;57(9):1082-8. doi: 10.1364/josa.57.001082.
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Pathophysiologic basis of amblyopia and of its treatment.弱视及其治疗的病理生理基础。
Am J Ophthalmol. 1969 Jan;67(1):1-12. doi: 10.1016/0002-9394(69)90002-6.
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Flicker and pattern detection: a comparison of thresholds.闪烁与图案检测:阈值比较
J Opt Soc Am. 1972 Mar;62(3):446-8. doi: 10.1364/josa.62.000446.
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Loss of a specific cell type from dorsal lateral geniculate nucleus in visually deprived cats.
J Neurophysiol. 1972 Jul;35(4):532-41. doi: 10.1152/jn.1972.35.4.532.

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