Rognstad R
Biochim Biophys Acta. 1980 Feb 21;628(1):116-8. doi: 10.1016/0304-4165(80)90357-8.
Both ethyl hydrazinoacetate and aminooxyacetate strongly inhibit gluconeogenesis from L-lactate, but not from pyruvate or fructose, in rat hepatocytes. Ethyl hydrazinoacetate partially inhibits gluconeogenesis from polyols, and also partially inhibits ethanol oxidation. In contrast to results obtained with aminooxyacetate, increasing the ethyl hydrazinoacetate concentration from 0.2 to 2 mM does not tend to diminish the inhibitory effect of this transaminase inhibitor on ethanol or polyol utilization.
在大鼠肝细胞中，乙酸乙酯肼和氨氧基乙酸都强烈抑制由L-乳酸生成葡萄糖的过程，但不抑制由丙酮酸或果糖生成葡萄糖的过程。乙酸乙酯肼部分抑制多元醇生成葡萄糖的过程，也部分抑制乙醇氧化。与氨氧基乙酸的结果相反，将乙酸乙酯肼的浓度从0.2 mM提高到2 mM，并不倾向于减弱这种转氨酶抑制剂对乙醇或多元醇利用的抑制作用。
