Lee D J, Leibel S, Shiels R, Sanders R, Siegelman S, Order S
Cancer. 1980 Feb 15;45(4):724-7. doi: 10.1002/1097-0142(19800215)45:4<724::aid-cncr2820450419>3.0.co;2-9.
Forty-four consecutive patients with potentially curable carcinoma of the prostate were localized with an Old Delft Simulator with the methods described by Bagshaw. The isocenter and the treatment portal were marked on the skin of the patient. Subsequently, the adequacy of the portal was checked by ultrasonography and/or CT scanning. Of 30 patients who underwent ultrasonography, five patients (17%) were found to have tumor extending beyond the initially simulated treatment portals. Using CT scanning, three of 22 patients were found to have tumor extending beyond the initially simulated portals. As a result, 1-2 cm were added to the initially simulated treatment portals for adequate coverage of the tumor volumes. Eight of our 44 patients underwent both studies and results were similar with ultrasonography and CT scanning. Only patients in the group presenting with clinical stage C disease had modifications of the initially simulated treatment portal. It is recommended that conventional simulation should be done first in order to establish the isocenter and treatment volume, which then should be confirmed by ultrasonography or CT scanning.
连续44例可能治愈的前列腺癌患者,采用Old Delft模拟器,按照巴格肖描述的方法进行定位。等中心和治疗野在患者皮肤上标记出来。随后,通过超声检查和/或CT扫描检查野的充分性。在接受超声检查的30例患者中,5例(17%)发现肿瘤超出最初模拟的治疗野。使用CT扫描时,22例患者中有3例发现肿瘤超出最初模拟的野。因此,在最初模拟的治疗野上增加1 - 2厘米,以充分覆盖肿瘤体积。我们的44例患者中有8例同时接受了这两项检查,超声检查和CT扫描的结果相似。只有临床分期为C期的患者组对最初模拟的治疗野进行了调整。建议首先进行传统模拟以确定等中心和治疗体积,然后通过超声检查或CT扫描进行确认。