Liebner E J, Stefani S
Cancer. 1980 Feb 15;45(4):728-34. doi: 10.1002/1097-0142(19800215)45:4<728::aid-cncr2820450420>3.0.co;2-n.
One hundred forty-nine lymphograms from patients with localized carcinomas of the prostate were interpreted by a referee radiologist without the benefit of clinical stage, grade of tumor, or the result of staging pelvic node dissection. The lymphogram was able to detect 30 of 35 (86%) positive nodal metastases and confirm 90 of 114 (79%) negative nodal biopsies. The internal iliac nodal biopsies were positive as a single finding in only 7 of 54 (13%) patients. The total external iliac nodal involvement was 41 of 54 (76%). High-grade prostate cancer patients have twice the incidence of positive nodal biopsies and lymphograms. Lymphography detected 43% of positive nodal patients with normal acid phosphatase and 69% of positive nodal patients with elevated acid phosphatase determinations. The lymphogram and tumor grade (prostate) are considered significant potential predictors of lymph node biopsy result. Finally, the incidence of nodal metastasis in localized prostatic cancer from surgical and histologically confirmed lymphogram series is reviewed with the concept of sensitivity and specificity of the lymphogram.
一位放射科主检医师对149例前列腺局限性癌患者的淋巴造影进行解读，解读时未参考临床分期、肿瘤分级或盆腔淋巴结清扫分期结果。淋巴造影能够检测出35例阳性淋巴结转移中的30例（86%），并证实114例阴性淋巴结活检中的90例（79%）。在54例患者中，仅有7例（13%）患者的髂内淋巴结活检结果单独显示为阳性。髂外淋巴结总的受累情况为54例中的41例（76%）。高级别前列腺癌患者淋巴结活检和淋巴造影阳性的发生率是其他患者的两倍。淋巴造影检测出43%酸性磷酸酶正常的阳性淋巴结患者以及69%酸性磷酸酶测定值升高的阳性淋巴结患者。淋巴造影和肿瘤分级（前列腺）被认为是淋巴结活检结果的重要潜在预测指标。最后，结合淋巴造影的敏感性和特异性概念，对手术及组织学确诊的淋巴造影系列中局限性前列腺癌淋巴结转移的发生率进行了回顾。
