红细胞增多症中P50值的估计值与测定值
Estimated and determined P50 values in erythrocytosis.
作者信息
Neilan B A, Gunter P, Adams A B, Johnson P B
出版信息
Chest. 1980 Apr;77(4):572-4. doi: 10.1378/chest.77.4.572.
Actual determination of the position of the oxygen-hemoglobin dissociation curve (P50) was compared to three methods of estimating P50 in 20 patients with erythrocytosis. There was a significant correlation between determined and estimated P50 values for each of the methods studied. Furthermore, four patients with high affinity hemoglobins were readily distinguished from the other patients by estimating P50. The data suggest that calculating P50 is reliable and may replace the need for actual measurement.
对20例红细胞增多症患者，将氧合血红蛋白解离曲线位置（P50）的实际测定结果与三种估算P50的方法进行了比较。在所研究的每种方法中，测定的P50值与估算的P50值之间均存在显著相关性。此外，通过估算P50，可轻松将4例高亲和力血红蛋白患者与其他患者区分开来。这些数据表明，计算P50是可靠的，可能无需进行实际测量。
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