儿童播散性非典型分枝杆菌病——一例海分枝杆菌感染病例

Disseminated atypical mycobacteriosis in a child--a case of Mycobacterium sculoflaseum.

作者信息

Yun K, Matsuo T, Kohno S, Ikeda T, Sakai M, Yoshimoto M, Nakashita Y

出版信息

Acta Pathol Jpn. 1978 Sep;28(5):751-8. doi: 10.1111/j.1440-1827.1978.tb00914.x.

DOI:10.1111/j.1440-1827.1978.tb00914.x

Abstract

A case of disseminated mycobacterial disease caused by mycobacterium sculoflaceum is presented in a three-year-old female. Atypical acid-fast organisms were found in cultures from the tissue of lymph node and bone marrow, gastric juice and feces. Histologically the mesenteric lymph nodes contained numerous large macrophages which had large numbers of acid-fast bacilli. Caseation necrosis was absent. Distinguishing features are the extensive involvement of lymph nodes and bones and the preference for intracellular presence of acid-fast bacilli. Up to the present in Japan there are only 17 reported cases of atypical mycobacteriosis in children.

摘要

本文报告了一例由斯库洛弗分枝杆菌引起的播散性分枝杆菌病，患者为一名三岁女性。在淋巴结、骨髓、胃液和粪便组织培养物中发现了非典型抗酸菌。组织学检查显示，肠系膜淋巴结中有大量含有大量抗酸杆菌的大巨噬细胞，无干酪样坏死。其显著特征是淋巴结和骨骼广泛受累，以及抗酸杆菌倾向于存在于细胞内。截至目前，日本仅报告了17例儿童非典型分枝杆菌病病例。