人胎盘IgG受体的进一步特性研究。
Further characterization of IgG receptors from human placenta.
作者信息
Watabe H, Gitlin J I, Gitlin D
出版信息
J Biochem. 1980 Feb;87(2):393-7. doi: 10.1093/oxfordjournals.jbchem.a132759.
Abstract
A Cell membrane fraction from term human placenta was prepared by homogenization and ultracentrifugation. The fraction was found to bind both human IgG and human serum albumin. Maximal specific binding occurred at pH 5.2, and the amount of binding was dependent upon incubation time, temperature, buffer, and ionic strength. The binding of human serum albumin was inhibited by preincubation with H-IgG but the reverse did not happen.
摘要
通过匀浆和超速离心制备足月人胎盘的细胞膜组分。发现该组分能与人IgG和人血清白蛋白结合。最大特异性结合发生在pH 5.2时，结合量取决于孵育时间、温度、缓冲液和离子强度。人血清白蛋白的结合可通过与H-IgG预孵育而受到抑制，但反之则不成立。
Zotero 插件