Freeman R, Hambling M H
J Clin Pathol. 1980 Jan;33(1):28-32. doi: 10.1136/jcp.33.1.28.
The results of serological study of 40 cases of mumps virus infection are presented. Mumps virus was isolated from 20 of the patients studied and antibodies to the V antigen, the S antigen, and the haemagglutination antigen were performed in all cases. Analysis of these results shows that estimation of all three types of antibody is necessary to confirm the diagnosis in the maximum number of instances and that the long-accepted view that a characteristic pattern of antibody response is typical of the acute illness (namely, anti-S appearing earlier and in greater titre than anti-V) is questionable.
本文呈现了对40例腮腺炎病毒感染患者的血清学研究结果。在所研究的患者中,有20例分离出了腮腺炎病毒,并且对所有病例都检测了针对V抗原、S抗原和血凝抗原的抗体。对这些结果的分析表明,在大多数情况下,要确诊需要对所有三种类型的抗体进行评估,而且长期以来被接受的观点,即抗体反应的特征模式是急性疾病的典型表现(即抗S抗体比抗V抗体出现更早且滴度更高)是值得怀疑的。