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奇异的皮肤神经纤维瘤

Bizarre cutaneous neurofibromas.

作者信息

King D T, Barr R J

出版信息

J Cutan Pathol. 1980 Feb;7(1):21-31. doi: 10.1111/j.1600-0560.1980.tb00973.x.

Abstract

Bizarre cutaneous neurofibroma is an uncommon benign neoplasm. Microscopically, it is usually characterized by stellate and polyhedral cells embedded in a myxoid stroma, and less commonly by solid sheets of epithelioid cells. Cellular pleomorphism and mitotic figures are regular features and have resulted in erroneous diagnosis of malignancy. The mucinous material has the staining characteristics of a sulfated mucosubstance, probably chondroitin sulfate B. Terms previously applied to this lesion include nerve sheath myxoma. Pacinian neurofibroma, myxoid neurofibroma, and neurotheceoma.

摘要

奇异皮肤神经纤维瘤是一种罕见的良性肿瘤。在显微镜下,它通常的特征是星状和多面体细胞嵌入黏液样基质中,较少见的是上皮样细胞的实性片块。细胞多形性和核分裂象是常见特征,这导致了对恶性肿瘤的错误诊断。黏液物质具有硫酸化黏液物质的染色特征,可能是硫酸软骨素B。以前用于该病变的术语包括神经鞘黏液瘤、帕西尼神经纤维瘤、黏液样神经纤维瘤和神经鞘瘤。

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