Fabrizi G, Porfiri B, Borgioli M, Serri F
J Cutan Pathol. 1980 Feb;7(1):8-20. doi: 10.1111/j.1600-0560.1980.tb00972.x.
A case of lipoid proteinosis was subjected to clinical, histologic and electron microscopic study. Palpebral biopsies showed a large dermal infiltration composed of closely interwoven granulo-filamentous material in the superficial and deep dermis. Collagen fibers were normal. Fibroblasts seemed to play an active role in the synthesis of this accumulating substance. Around the dermal capillaries there was a prominent concentric multilamination of the basal lamina which was considered a reaction of the endothelial cells to the irritation caused by compression of the accumulating substance.
对一例类脂蛋白沉积症患者进行了临床、组织学和电子显微镜研究。眼睑活检显示,在真皮浅层和深层有大量由紧密交织的颗粒状细丝物质构成的真皮浸润。胶原纤维正常。成纤维细胞似乎在这种蓄积物质的合成中发挥了积极作用。在真皮毛细血管周围,基膜有明显的同心多层结构,这被认为是内皮细胞对蓄积物质压迫所引起刺激的一种反应。