• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Inhibitors of polyamine biosynthesis. 8. Irreversible inhibition of mammalian S-adenosyl-L-methionine decarboxylase by substrate analogues.

作者信息

Pankaskie M, Abdel-Monem M M

出版信息

J Med Chem. 1980 Feb;23(2):121-7. doi: 10.1021/jm00176a004.

DOI:10.1021/jm00176a004
PMID:7359525
Abstract
摘要

相似文献

1
Inhibitors of polyamine biosynthesis. 8. Irreversible inhibition of mammalian S-adenosyl-L-methionine decarboxylase by substrate analogues.多胺生物合成抑制剂。8. 底物类似物对哺乳动物S-腺苷-L-甲硫氨酸脱羧酶的不可逆抑制作用。
J Med Chem. 1980 Feb;23(2):121-7. doi: 10.1021/jm00176a004.
2
Inhibition of S-adenosylmethionine decarboxylase from rat liver by synthetic decarboxylated S-adenosylmethionine and its analogs.合成的脱羧S-腺苷甲硫氨酸及其类似物对大鼠肝脏S-腺苷甲硫氨酸脱羧酶的抑制作用。
Chem Pharm Bull (Tokyo). 1980 Jul;28(7):2232-4. doi: 10.1248/cpb.28.2232.
3
Synthesis and biochemical properties of chemically stable product analogues of the reaction catalyzed by S-adenosyl-L-methionine decarboxylase.S-腺苷-L-甲硫氨酸脱羧酶催化反应的化学稳定产物类似物的合成及生化特性
J Med Chem. 1982 May;25(5):550-6. doi: 10.1021/jm00347a014.
4
Inhibitors of polyamine biosynthesis VII: Evaluation of pyruvate derivatives as inhibitors of S-adenosyl-L-methionine decarboxylase.多胺生物合成抑制剂VII：丙酮酸衍生物作为S-腺苷-L-甲硫氨酸脱羧酶抑制剂的评估
J Pharm Sci. 1980 Sep;69(9):1000-4. doi: 10.1002/jps.2600690904.
5
Inhibitors of S-adenosylmethionine decarboxylase.S-腺苷甲硫氨酸脱羧酶抑制剂
Methods Enzymol. 1983;94:239-47. doi: 10.1016/s0076-6879(83)94042-9.
6
Irreversible inhibition of putrescine-stimulated S-adenosyl-L-methionine decarboxylase by berenil and pentamidine.贝尼尔和喷他脒对腐胺刺激的S-腺苷-L-蛋氨酸脱羧酶的不可逆抑制作用。
Biochem J. 1985 Oct 1;231(1):165-9. doi: 10.1042/bj2310165.
7
Comparison of inhibitors of S-adenosylmethionine decarboxylase from different species.不同物种间S-腺苷甲硫氨酸脱羧酶抑制剂的比较。
Biochem J. 1983 Aug 1;213(2):495-502. doi: 10.1042/bj2130495.
8
Accumulation of decarboxylated S-adenosyl-L-methionine in mammalian cells as a consequence of the inhibition of putrescine biosynthesis.由于腐胺生物合成受到抑制，哺乳动物细胞中脱羧S-腺苷-L-甲硫氨酸的积累。
Eur J Biochem. 1982 Apr;123(3):499-504. doi: 10.1111/j.1432-1033.1982.tb06559.x.
9
Putrescine-insensitive S-adenosyl-L-methionine decarboxylase from Tetrahymena pyriformis.来自梨形四膜虫的腐胺不敏感型S-腺苷-L-甲硫氨酸脱羧酶。
Acta Chem Scand B. 1975;29(9):932-6. doi: 10.3891/acta.chem.scand.29b-0932.
10
Inhibition of S-adenosyl methionine decarboxylase by guanethidine.胍乙啶对S-腺苷甲硫氨酸脱羧酶的抑制作用。
Biochem Pharmacol. 1980 Jan 1;29(1):113-5. doi: 10.1016/0006-2952(80)90253-1.

引用本文的文献

1
The Bucherer-Bergs Multicomponent Synthesis of Hydantoins-Excellence in Simplicity.布赫雷尔-伯格斯多元醇合成海因-简单的卓越。
Molecules. 2021 Jun 30;26(13):4024. doi: 10.3390/molecules26134024.
2
Complexes of Thermotoga maritimaS-adenosylmethionine decarboxylase provide insights into substrate specificity.嗜热栖热菌S-腺苷甲硫氨酸脱羧酶复合物为底物特异性提供了见解。
Acta Crystallogr D Biol Crystallogr. 2010 Feb;66(Pt 2):181-9. doi: 10.1107/S090744490904877X. Epub 2010 Jan 22.
3
Structural biology of S-adenosylmethionine decarboxylase.
S-腺苷甲硫氨酸脱羧酶的结构生物学。
Amino Acids. 2010 Feb;38(2):451-60. doi: 10.1007/s00726-009-0404-y. Epub 2009 Dec 8.
4
Role of the sulfonium center in determining the ligand specificity of human s-adenosylmethionine decarboxylase.锍中心在决定人S-腺苷甲硫氨酸脱羧酶配体特异性中的作用。
Biochemistry. 2009 Jul 14;48(27):6423-30. doi: 10.1021/bi900590m.
5
New insights into the design of inhibitors of human S-adenosylmethionine decarboxylase: studies of adenine C8 substitution in structural analogues of S-adenosylmethionine.人类S-腺苷甲硫氨酸脱羧酶抑制剂设计的新见解：S-腺苷甲硫氨酸结构类似物中腺嘌呤C8取代的研究
J Med Chem. 2009 Mar 12;52(5):1388-407. doi: 10.1021/jm801126a.
6
In vivo mechanism-based inactivation of S-adenosylmethionine decarboxylases from Escherichia coli, Salmonella typhimurium, and Saccharomyces cerevisiae.基于体内机制对来自大肠杆菌、鼠伤寒沙门氏菌和酿酒酵母的S-腺苷甲硫氨酸脱羧酶的失活作用
Proc Natl Acad Sci U S A. 2001 Sep 11;98(19):10578-83. doi: 10.1073/pnas.181341198. Epub 2001 Aug 28.
7
Comparison of inhibitors of S-adenosylmethionine decarboxylase from different species.不同物种间S-腺苷甲硫氨酸脱羧酶抑制剂的比较。
Biochem J. 1983 Aug 1;213(2):495-502. doi: 10.1042/bj2130495.
8
Metabolic activation and detoxication of nephrotoxic cysteine and homocysteine S-conjugates.肾毒性半胱氨酸和同型半胱氨酸S-共轭物的代谢活化与解毒作用。
Proc Natl Acad Sci U S A. 1986 Apr;83(8):2667-71. doi: 10.1073/pnas.83.8.2667.
9
Cellular characterization of a new irreversible inhibitor of S-adenosylmethionine decarboxylase and its use in determining the relative abilities of individual polyamines to sustain growth and viability of L1210 cells.一种新型S-腺苷甲硫氨酸脱羧酶不可逆抑制剂的细胞特性及其在确定单个多胺维持L1210细胞生长和活力的相对能力中的应用。
Biochem J. 1989 Apr 15;259(2):325-31. doi: 10.1042/bj2590325.
10
Cure of Trypanosoma brucei brucei and Trypanosoma brucei rhodesiense infections in mice with an irreversible inhibitor of S-adenosylmethionine decarboxylase.用S-腺苷甲硫氨酸脱羧酶不可逆抑制剂治愈小鼠体内的布氏布氏锥虫和布氏罗德西亚锥虫感染。
Antimicrob Agents Chemother. 1990 Aug;34(8):1485-90. doi: 10.1128/AAC.34.8.1485.