Spohr U, Schneider H W, Streicher E, Schrack R, Ritz E
Nephron. 1980;25(3):121-6. doi: 10.1159/000181767.
Plasma dopamine beta-hydroxylase (DBH) activity was studied in control patients (n = 70), in patients on maintenance hemodialysis (n = 79) and in patients on maintenance hemofiltration (n = 19). DBH activity was significantly lower in patients on hemodialysis (32.4 +/- 20.6 IU) and hemofiltration (32.8 +/- 29.7 IU) than in control individuals (50.0 +/- 29.3 IU). Sequential measurements of DBH in patients on maintenance hemofiltration failed to show a fall of plasma DBH with time. 7 patients were studied during one session of hemodialysis and one session of hemofiltration. External fluid balance was identical. The change of DBH during hemodialysis and hemofiltration was not significantly different. Such rise of DBH as occurs may entirely be accounted for by hemoconcentration.
对70名对照患者、79名维持性血液透析患者和19名维持性血液滤过患者的血浆多巴胺β-羟化酶（DBH）活性进行了研究。血液透析患者（32.4±20.6 IU）和血液滤过患者（32.8±29.7 IU）的DBH活性显著低于对照个体（50.0±29.3 IU）。对维持性血液滤过患者的DBH进行连续测量，未发现血浆DBH随时间下降。对7名患者在一次血液透析和一次血液滤过过程中进行了研究。外部液体平衡相同。血液透析和血液滤过期间DBH的变化无显著差异。所出现的DBH升高可能完全是由血液浓缩引起的。
