McCarty K S, Kesterson G H, Barton T K, Seigler H F, Georgiade N G
Surg Gynecol Obstet. 1980 Apr;150(4):545-7.
In a prospective analysis of 291 specimens taken at mastectomy for carcinoma, 48 contained tumor in the nipple-areola complex. The characteristics of greater tumor size, higher frequency of lymph node involvement, midbreast tumor location and multifocality of tumor correlated well with the probability of involvement of the nipple. The findings emphasize the importance of close clinical and histopathologic examination of the nipple and areola when preservation of the nipple is being considered.
在一项对291例因癌接受乳房切除术的标本进行的前瞻性分析中，48例乳头乳晕复合体中含有肿瘤。肿瘤体积较大、淋巴结受累频率较高、肿瘤位于乳房中部以及肿瘤多灶性等特征与乳头受累的可能性密切相关。这些发现强调了在考虑保留乳头时，对乳头和乳晕进行仔细临床和组织病理学检查的重要性。
