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经尿道前列腺切除术后低钠血症所致昏迷

Coma from hyponatremia following transurethral resection of prostate.

作者信息

Henderson D J, Middleton R G

出版信息

Urology. 1980 Mar;15(3):267-71. doi: 10.1016/0090-4295(80)90441-0.

DOI:10.1016/0090-4295(80)90441-0
PMID:7361356
Abstract

Even though hyponatremia may occur following transurethral resection of the prostate (TURP), only 14 patients of a large TURP population deteriorated to a comatose state as a result of hyponatremia. These patients were generally older, with larger prostates, and longer resection times than the average for transurethral resection of the prostate. They also consistently had serum sodium levels postoperatively of near 120 mEq./L. or below. It was noted that obtundation can occur immediately or be delayed several hours. Even though no deaths occurred, awareness of the possibility of post-TURP hyponatremia and prompt treatment with hypertonic saline were shown to reduce morbidity significantly.

摘要

尽管经尿道前列腺电切术(TURP)后可能会发生低钠血症,但在大量接受TURP手术的患者中,只有14例因低钠血症而恶化至昏迷状态。这些患者通常年龄较大,前列腺体积较大,手术切除时间比前列腺经尿道切除术的平均时间更长。他们术后的血清钠水平也一直接近120 mEq./L或更低。值得注意的是,意识模糊可能立即出现,也可能延迟数小时。尽管没有死亡病例,但认识到TURP术后低钠血症的可能性并及时用高渗盐水治疗可显著降低发病率。

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