Giles C J, Smith I M, Baskerville A J, Brothwell E
Vet Rec. 1980 Jan 12;106(2):25-8. doi: 10.1136/vr.106.2.25.
Three distinct patterns of infection with Bordetella (Alcaligenes) bronchiseptica were found in groups of 12 to 24 pigs born in 1977-78 in 12 herds in southern England. In five of these, heavy bordetella infection of a substantial proportion of unweaned piglets persisted to a variable extent until slaughter. Clinical disease and severely atrophied turbinates were most marked in these groups. In three other herds the infection first appeared soon after weaning and occasionally persisted until slaughter. Clinical disease occurred in only one of these other groups and conchal atrophy at slaughter was moderate. In the groups of the four remaining herds there was no clinical disease and conchal atrophy at slaughter was slight, infection appearing only late in the weaning, or even the fattening, stages. These varying patterns suggest that immunological phenomena were involved in the infection in the least affected herds and that such responses might, if reproducible artificially, provide a better means of control of this disease in badly affected herds than the available forms of chemotherapy.
在1977年至1978年出生于英格兰南部12个猪群中的12至24头猪的群体中，发现了支气管败血博德特氏菌（产碱杆菌）的三种不同感染模式。在其中五个猪群中，相当比例的未断奶仔猪的严重博德特氏菌感染在不同程度上持续到屠宰。这些猪群中临床疾病和严重萎缩的鼻甲最为明显。在其他三个猪群中，感染在断奶后不久首次出现，偶尔持续到屠宰。这些其他猪群中只有一个出现了临床疾病，屠宰时鼻甲萎缩程度适中。在其余四个猪群中，没有临床疾病，屠宰时鼻甲萎缩轻微，感染仅在断奶后期甚至育肥阶段出现。这些不同模式表明，免疫现象参与了受影响最小的猪群的感染，并且如果能够人工重现这种反应，那么与现有的化疗形式相比，这可能为控制受严重影响猪群中的这种疾病提供更好的方法。
