Christensen N J, Vestergaard P, Sørensen T, Rafaelsen O J
Acta Psychiatr Scand. 1980 Feb;61(2):178-82. doi: 10.1111/j.1600-0447.1980.tb00577.x.
Mean adrenaline concentration in cerebrospinal fluid measured by a sensitive and specific isotope-derivative assay was significantly lower in 15 depressed patients during illness compared with 18 control subjects. At the time of recovery cerebrospinal adrenaline levels had increased markedly to normal levels. Cerebrospinal fluid noradrenaline did not differ in patients compared with controls. The present findings suggest that adrenaline as a neurotransmitter may be involved in affective disorders.
通过一种灵敏且特异的同位素衍生分析法测得，15名抑郁症患者在患病期间脑脊液中的肾上腺素平均浓度显著低于18名对照受试者。在康复时，脑脊液中的肾上腺素水平已显著升高至正常水平。与对照组相比，患者脑脊液中的去甲肾上腺素并无差异。目前的研究结果表明，肾上腺素作为一种神经递质可能与情感障碍有关。
