Martínez F, Castillo J, Pardo J, Lema M, Noya M
Department of Neurology, Hospital General de Galicia, Clinico Universitario, Santiago de Compostela, Spain.
J Neurol Neurosurg Psychiatry. 1993 Oct;56(10):1119-21. doi: 10.1136/jnnp.56.10.1119.
There is clinical and pharmacological evidence of the existence of sympathetic dysfunction in migraine. Adrenaline and noradrenaline concentrations were determined in plasma and CSF of patients during attacks of common or classic migraine, comparing them with controls suffering from stress. Plasma noradrenaline levels were significantly lower in the patients with common migraine than in controls (p < 0.05). Other catecholamine levels in plasma and CSF in both migraine groups were only slightly lower than in controls. Our results suggest that central sympathetic dysfunction exists in patients with migraine.
有临床和药理学证据表明偏头痛患者存在交感神经功能障碍。在普通型或典型偏头痛发作期间，测定了患者血浆和脑脊液中的肾上腺素和去甲肾上腺素浓度，并将其与遭受压力的对照组进行比较。普通偏头痛患者的血浆去甲肾上腺素水平显著低于对照组（p < 0.05）。两个偏头痛组的血浆和脑脊液中的其他儿茶酚胺水平仅略低于对照组。我们的结果表明偏头痛患者存在中枢交感神经功能障碍。
