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老年体位性低血压:是神经系统疾病还是血管疾病?

Postural hypotension in old age: is it a disorder of the nervous system or of blood vessels?

作者信息

MacLennan W J, Hall M R, Timothy J I

出版信息

Age Ageing. 1980 Feb;9(1):25-32. doi: 10.1093/ageing/9.1.25.

DOI:10.1093/ageing/9.1.25
PMID:7361633
Abstract

Beat to beat variation, postural changes in blood pressure and thresholds for vibration sense were measured in 10 young adults and 186 old people living at home. There was a reduction in beat to beat variation, but and increase in postural changes in blood pressure and thresholds for vibration sense in the elderly. Within age and sex groups, there was no correlation between beat to beat variation, postural changes in blood pressure and thresholds for vibration sense, but a strong positive correlation between postural changes in blood pressure and lying systolic pressures. This suggests that, in old age, a change in the structure of the vascular tree may be more important than autonomic dysfunction, as a determinant of postural hypotension.

摘要

对10名年轻成年人和186名居家老人测量了逐搏变化、血压的体位变化以及振动觉阈值。老年人的逐搏变化减少,但血压的体位变化和振动觉阈值增加。在年龄和性别组内,逐搏变化、血压的体位变化与振动觉阈值之间无相关性,但血压的体位变化与卧位收缩压之间存在强正相关。这表明,在老年时,血管树结构的改变可能比自主神经功能障碍更重要,是体位性低血压的决定因素。

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