Harburg E, Gleibermann L, Roeper P, Schork M A, Schull W J
Am J Public Health. 1978 Dec;68(12):1177-83. doi: 10.2105/ajph.68.12.1177.
Census areas in Detroit were ranked for their stress scores based on instability (e.g., crime, marital break up) and socioeconomic status. Four areas were selected for detailed study: 1) high stress, population predominantly black, 2) white, 3) low stress, population predominantly black, 4) white. A sample was drawn from each area of persons of the predominant race, 25-60 years old, married and living with spouse, and having relatives in the Detroit Area. Nurses interviewed such persons; three blood pressure readings were taken during the first half-hour of medical history, and skin color was rated. Results show that darker skin color, for black males especially, is related to higher pressure, independently of nine control variables (e.g., age, weight, socioeconomic status, etc.). However, younger black males (25-39 years of age) in high stress areas had higher pressure than counterparts in low stress areas, regardless of skin color and relative weight; for older black males (40-59 years of age) darker skin color was correlated with higher pressure, regardless of relative weight or stress area. For 35 blacks whose fathers were from the West Indies, pressures were higher than those with American-born fathers. These findings suggest that varied gene mixtures may be related to blood pressure levels and that skin color, an indicator of possible metabolic significance, combines with socially induced stress to induce higher blood pressures in lower class American blacks.
根据不稳定因素(如犯罪、婚姻破裂)和社会经济地位,对底特律的普查区域进行了压力评分排名。选取了四个区域进行详细研究:1)高压力区,人口以黑人为主;2)白人区;3)低压力区,人口以黑人为主;4)白人区。从每个区域抽取了主要种族的样本,年龄在25至60岁之间,已婚且与配偶同住,并且在底特律地区有亲属。护士对这些人进行了访谈;在病史询问的前半小时内测量了三次血压,并对肤色进行了评级。结果表明,较深的肤色,尤其是黑人男性的,与较高的血压有关,独立于九个控制变量(如年龄、体重、社会经济地位等)。然而,高压力区的年轻黑人男性(25至39岁)的血压高于低压力区的同龄人,无论肤色和相对体重如何;对于年长的黑人男性(40至59岁),较深的肤色与较高的血压相关,无论相对体重或压力区域如何。对于35名父亲来自西印度群岛的黑人,其血压高于父亲出生在美国的黑人。这些发现表明,不同的基因组合可能与血压水平有关,并且肤色作为可能具有代谢意义的指标,与社会诱导的压力相结合,导致美国下层阶级黑人的血压升高。