一种用于检测非那西丁、对乙酰氨基酚、2-乙酰氨基芴及其他异羟肟酸的N-羟基衍生物的简单高效液相色谱分析法。 - Suppr | 超能文献

A simple high-pressure liquid chromatographic assay for the N-hydroxy derivatives of phenacetin, acetaminophen, 2-acetylaminofluorene, and other hydroxamic acids.

作者信息

Hinson J A, Pohl L R, Gillette J R

出版信息

Anal Biochem. 1980 Jan 15;101(2):462-7. doi: 10.1016/0003-2697(80)90213-4.

DOI:10.1016/0003-2697(80)90213-4

Abstract

摘要

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A simple high-pressure liquid chromatographic assay for the N-hydroxy derivatives of phenacetin, acetaminophen, 2-acetylaminofluorene, and other hydroxamic acids.一种用于检测非那西丁、对乙酰氨基酚、2-乙酰氨基芴及其他异羟肟酸的N-羟基衍生物的简单高效液相色谱分析法。

Anal Biochem. 1980 Jan 15;101(2):462-7. doi: 10.1016/0003-2697(80)90213-4.

2

Mutagenicity of N-hydroxy-2-acetylaminofluorene and N-hydroxy-phenacetin and their respective deacetylated metabolites in nitroreductase deficient Salmonella TA98FR and TA100FR.N-羟基-2-乙酰氨基芴和N-羟基非那西汀及其各自的脱乙酰代谢产物在缺乏硝基还原酶的鼠伤寒沙门氏菌TA98FR和TA100FR中的致突变性。

Carcinogenesis. 1982;3(2):167-70. doi: 10.1093/carcin/3.2.167.

3

Metabolism of N-hydroxy-2-acetylaminofluorene and N-hydroxy-phenacetin by guinea pig liver microsomal enzymes.豚鼠肝微粒体酶对N-羟基-2-乙酰氨基芴和N-羟基非那西汀的代谢作用。

Carcinogenesis. 1985 Apr;6(4):495-9. doi: 10.1093/carcin/6.4.495.

4

Metabolic activation and genotoxicity of N-hydroxy-2-acetylaminofluorene and N-hydroxyphenacetin derivatives in Reuber (H4-II-E) hepatoma cells.N-羟基-2-乙酰氨基芴和N-羟基非那西汀衍生物在鲁伯（H4-II-E）肝癌细胞中的代谢活化及遗传毒性

Cancer Res. 1984 Mar;44(3):1098-104.

5

N-hydroxy-2-acetylaminofluorene as effective inhibitor of aldehyde oxidase.N-羟基-2-乙酰氨基芴作为醛氧化酶的有效抑制剂。

Biochem Biophys Res Commun. 1986 Jul 16;138(1):312-7. doi: 10.1016/0006-291x(86)90281-0.

6

Reductase activity of aldehyde oxidase toward the carcinogen N-hydroxy-2-acetylaminofluorene and the related hydroxamic acids.醛氧化酶对致癌物N-羟基-2-乙酰氨基芴及相关异羟肟酸的还原酶活性。

Biochem Mol Biol Int. 1994 Dec;34(6):1197-203.

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N-acetyltransferase multiplicity and the bioactivation of N-arylhydroxamic acids by hamster hepatic and intestinal enzymes.

Carcinogenesis. 1986 May;7(5):697-702. doi: 10.1093/carcin/7.5.697.

8

Metabolic structure-activity relationship for a homologous series of phenacetin analogs.非那西丁类似物同系物的代谢构效关系。

J Pharmacol Exp Ther. 1979 Apr;209(1):20-4.

9

Reduction of N-hydroxy-2-acetylaminofluorene by liver microsomes.肝脏微粒体对N-羟基-2-乙酰氨基芴的还原作用。

Biochem Pharmacol. 1980 Aug 15;29(16):2183-8. doi: 10.1016/0006-2952(80)90196-3.

10

Decreased toxicity of the N-methyl analogs of acetaminophen and phenacetin.对乙酰氨基酚和非那西丁的N-甲基类似物毒性降低。

Res Commun Chem Pathol Pharmacol. 1978 Oct;22(1):61-71.

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The development and hepatotoxicity of acetaminophen: reviewing over a century of progress.对乙酰氨基酚的发展及其肝毒性：回顾一个多世纪的进展。

Drug Metab Rev. 2020 Nov;52(4):472-500. doi: 10.1080/03602532.2020.1832112. Epub 2020 Oct 14.