Montgomerie J Z, Ota J K
Arch Intern Med. 1980 Apr;140(4):525-7.
Of 41 patients with Klebsiella bacteremia studied, most were newborn or elderly and only one patient had community-acquired infection. The incidence of bacteremia was evenly distributed over 16 months, except that infections in the newborns occurred in a cluster. The initial site of infection resulting in bacteremia was urinary tract (27%), gastrointestinal tract (24%), intravenous sites (20%), and pulmonary system (15%). Mortality was influenced by the underlying disease, the age of the patients, and site of initial infection. In patients with nonfatal underlying disease, deaths occurred only in patients with pulmonary or abdominal infections and did not occur in patients in whom the portal of entry was the urinary tract or intravenous sites. Single antibiotic therapy with aminoglycoside was adequate in this latter group.
在研究的41例克雷伯菌血症患者中，大多数是新生儿或老年人，只有1例为社区获得性感染。菌血症的发病在16个月内分布均匀，只是新生儿感染呈聚集性发生。导致菌血症的初始感染部位为泌尿系统（27%）、胃肠道（24%）、静脉穿刺部位（20%）和肺部系统（15%）。死亡率受基础疾病、患者年龄和初始感染部位的影响。在患有非致命性基础疾病的患者中，死亡仅发生在肺部或腹部感染患者中，而感染入口为泌尿系统或静脉穿刺部位的患者未出现死亡。后一组患者使用氨基糖苷类单一抗生素治疗就足够了。
