Mitchell F K
J Gen Intern Med. 1987 Jan-Feb;2(1):36-9. doi: 10.1007/BF02596249.
In a suburban hospital, 38 adult patients with community-acquired bacteremic infections and without "rapidly fatal" disease were studied. In univariate analyses, the 31 patients discharged alive had higher initial temperatures, blood pressures, and calcium and albumin values, and lower immature leukocyte counts, and were treated sooner with appropriate antibiotics than those who died. With the exception of time elapsed before appropriate treatment, these factors were used in discriminant analysis to identify patients who would die during hospital admission from bacteremic infection. The resulting model, which had a sensitivity of 71% and a specificity of 68% in the first group of patients, was validated in a second cohort with a sensitivity of 40% and a specificity of 69%. This analysis presents a model that may allow clinicians to assess the risk of death from community-acquired bacteremic infections.
在一家郊区医院,对38例患有社区获得性菌血症感染且无“快速致命”疾病的成年患者进行了研究。在单因素分析中,31例存活出院的患者初始体温、血压、钙和白蛋白值较高,未成熟白细胞计数较低,且比死亡患者更早接受了适当的抗生素治疗。除了开始适当治疗前的时间外,这些因素被用于判别分析,以识别因菌血症感染而在住院期间死亡的患者。该模型在第一组患者中的敏感性为71%,特异性为68%,在第二组队列中进行验证时,敏感性为40%,特异性为69%。该分析提出了一个模型,可使临床医生评估社区获得性菌血症感染导致死亡的风险。