Cortin P, Archer D, Maumenee I H, Feiock K, Speros P
Br J Ophthalmol. 1980 Feb;64(2):127-34. doi: 10.1136/bjo.64.2.127.
Three middle-aged male patients are described with a peculiar patterned dystrophy of the macula. The basic lesions are discrete yellow plaques typically confined to the macular area and radiating from the fovea. They appear to be located at the level of the retinal pigment epithelium (RPE). With the passage of time some of the yellow plaques altered in extent and configuration, and atrophic changes appeared or extended. Visual acuity and electrophysiological tests are either normal or only moderately affected. The lesions appear to be distinct from the patterned dystrophies of the retina already described and from other conditions characterised by yellow or white deposits at the level of the RPE.
本文描述了三名患有黄斑区特殊图案状营养不良的中年男性患者。基本病变为离散的黄色斑块,通常局限于黄斑区并从中央凹放射状分布。它们似乎位于视网膜色素上皮(RPE)层。随着时间的推移,一些黄色斑块在范围和形态上发生改变,萎缩性改变出现或扩大。视力和电生理检查要么正常,要么仅受到中度影响。这些病变似乎与已描述的视网膜图案状营养不良以及其他以RPE层出现黄色或白色沉积物为特征的疾病不同。