Farsang C, Debreczeni L, Kerényi A, Takács L
Cardiology. 1980;65(2):65-84. doi: 10.1159/000170797.
Reactive hyperemia following occlusions of 15, 30, 60 and 120 sec duration was studied in the left coronary vascular bed of the isolated fibrillating dog heart perfused with arterial blood at constant pressure or constant volume. Except for repayment, linear correlations were found between occlusion time and the characteristics of reactive hyperemia. At a basal perfusion pressure of 50 mm Hg the postocclusion reaction was absent. The maximum hyperemic response was observed at 100 mm Hg, while on a further increase of perfusion pressure reactive hyperemia decreased. The postocclusion reaction was more marked but of briefer duration under constant pressure perfusion. The results can be explained by the joint effects of metabolic, myogenic, and physical factors on coronary vascular tone.
在以恒压或恒容方式用动脉血灌注的离体颤动犬心脏的左冠状动脉血管床中，研究了持续15、30、60和120秒的闭塞后的反应性充血。除了偿还外，发现闭塞时间与反应性充血特征之间存在线性相关性。在基础灌注压为50 mmHg时，闭塞后反应不存在。在100 mmHg时观察到最大充血反应，而随着灌注压进一步升高，反应性充血减少。在恒压灌注下，闭塞后反应更明显但持续时间更短。这些结果可以通过代谢、肌源性和物理因素对冠状动脉张力的联合作用来解释。
