Connolly T P, Noujaim A A, Man S F
Am Rev Respir Dis. 1978 Nov;118(5):965-8. doi: 10.1164/arrd.1978.118.5.965.
We describe a method to study simultaneously the transport of 2 different markers in the canine trachea. In our studies, we found that choice of radioisotopic label and variation in marker size from 3 to 180 micrometer did not affect the transport rate of basic anion exchange resin particles. Furthermore, anion exchange and acidic cation exchange particles of the same size had similar tracheal transport rates. This method may help to determine the influence of the physicochemical properties of markers on mucous transport.
我们描述了一种同时研究犬气管中两种不同标记物转运的方法。在我们的研究中，我们发现放射性同位素标记的选择以及标记物大小从3微米到180微米的变化并不影响碱性阴离子交换树脂颗粒的转运速率。此外，相同大小的阴离子交换颗粒和酸性阳离子交换颗粒具有相似的气管转运速率。这种方法可能有助于确定标记物的物理化学性质对黏液转运的影响。
