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新型强效镇痛药地佐辛的初步临床经验

Preliminary clinical experience with dezocine, a new potent analgesic.

作者信息

Oosterlinck W, Verbaeys A

出版信息

Curr Med Res Opin. 1980;6(7):472-4. doi: 10.1185/03007998009109470.

Abstract

The analgesic effect of a single intravenous dose of dezocine at various dosage levels was studied in 41 patients suffering from acute renal colic. Twenty milligrams was found to be a very effective dose. Out of 25 injections an excellent response was recorded on 21 occasions, with a mean duration of effect of 3.5 hours. In a further 3 patients, pain relief was considered as fair and of shorter duration. Pronounced dizziness was a nearly constant side-effect of the drug. There was no overall effect on blood pressure or heart rate.

摘要

在41例急性肾绞痛患者中研究了不同剂量单次静脉注射地佐辛的镇痛效果。发现20毫克是非常有效的剂量。在25次注射中,有21次记录到极佳的反应,平均起效持续时间为3.5小时。另外3例患者疼痛缓解效果一般且持续时间较短。明显头晕是该药几乎持续存在的副作用。对血压和心率无总体影响。

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