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人类宫颈中的精子储存:一项定量研究。

Sperm storage in the human cervix: a quantitative study.

作者信息

Insler V, Glezerman M, Zeidel L, Bernstein D, Misgav N

出版信息

Fertil Steril. 1980 Mar;33(3):288-93. doi: 10.1016/s0015-0282(16)44596-6.

DOI:10.1016/s0015-0282(16)44596-6
PMID:7364062
Abstract

Twenty-five women scheduled for hysterectomy for nonmalignant disease participated in the study. Sperm storage in endocervical crypts was examined in three groups of patients: nine women pretreated with estrogen and inseminated with normal semen, nine women pretreated with gestagen and inseminated with normal semen, and seven women pretreated with estrogen and inseminated with abnormal semen. The number of crypts containing spermatozoa (colonized crypts) and the sperm density per crypt were examined in serially sectioned cervices. In estrogen-pretreated cervices both the percentage of colonized crypts and the sperm density were significantly higher than in gestagen-pretreated cervices. Large and giant crypts proved to be the main storage facility for spermatozoa. The localization of crypts along the endocervical canal did not influence sperm storage. The quality of semen appeared to be of critical importance to sperm storage. The percentage of colonized crypts and sperm density were severly reduced in patients inseminated with abnormal semen.

摘要

25名计划因非恶性疾病行子宫切除术的女性参与了该研究。对三组患者的宫颈隐窝内精子储存情况进行了检查:9名接受雌激素预处理并授以正常精液的女性,9名接受孕激素预处理并授以正常精液的女性,以及7名接受雌激素预处理并授以异常精液的女性。在连续切片的宫颈中检查含有精子的隐窝数量(定植隐窝)和每个隐窝的精子密度。在接受雌激素预处理的宫颈中,定植隐窝的百分比和精子密度均显著高于接受孕激素预处理的宫颈。大隐窝和巨隐窝被证明是精子的主要储存场所。隐窝沿宫颈管的定位不影响精子储存。精液质量似乎对精子储存至关重要。授以异常精液的患者中,定植隐窝的百分比和精子密度严重降低。

相似文献

1
Sperm storage in the human cervix: a quantitative study.人类宫颈中的精子储存:一项定量研究。
Fertil Steril. 1980 Mar;33(3):288-93. doi: 10.1016/s0015-0282(16)44596-6.
2
Fertility, motility and penetration in cervical mucus of freeze-preserved human spermatozoa.冷冻保存的人类精子在宫颈黏液中的生育能力、活力及穿透能力。
Acta Obstet Gynecol Scand. 1973;52(3):205-10. doi: 10.3109/00016347309158316.
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The interaction of human spermatozoa with cervical mucus in vivo.人类精子与宫颈黏液在体内的相互作用。
Am J Obstet Gynecol. 1981 May 15;140(2):173-8. doi: 10.1016/0002-9378(81)90105-8.
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Endocrinological and physiological features after steroid treatment of male rats.雄性大鼠接受类固醇治疗后的内分泌学和生理学特征。
Arch Androl. 1978 Sep;1(4):311-20. doi: 10.3109/01485017808988351.
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The effect of estrogen and gestagen on the mucus production of human endocervical cells: a histochemical study.雌激素和孕激素对人宫颈内膜细胞黏液分泌的影响:一项组织化学研究。
Fertil Steril. 1982 Nov;38(5):580-5. doi: 10.1016/s0015-0282(16)46638-0.
6
Production of cervical mucus in ewes treated with exogenous progestagen and oestrogen.用外源性孕激素和雌激素处理的母羊宫颈黏液的产生。
Aust J Agric Res. 1972;23:473-81. doi: 10.1071/ar9720473.
7
Control of fertility with oral medication.口服药物控制生育。
West J Surg Obstet Gynecol. 1964 Jul-Aug;72:222-9.
8
Timing of onset of contraceptive effectiveness in Depo-Provera users: Part I. Changes in cervical mucus.醋酸甲羟孕酮使用者避孕效果开始的时间:第一部分。宫颈黏液的变化。
Fertil Steril. 1998 Feb;69(2):252-7. doi: 10.1016/s0015-0282(97)00477-9.
9
Sperm transport from the external cervical os to the fallopian tubes in women: a time and quantitation study.女性精子从宫颈外口向输卵管的运输:一项时间与定量研究。
Fertil Steril. 1973 Sep;24(9):655-61. doi: 10.1016/s0015-0282(16)39908-3.
10
Cervical mucus in estrous ewes after treatment with estrogen, progestogens and intrauterine devices.用雌激素、孕激素和宫内节育器处理后发情期母羊的宫颈黏液
J Anim Sci. 1977 Jan;44(1):102-5. doi: 10.2527/jas1977.441102x.

引用本文的文献

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Seminal Fluid Interaction with Female Reproductive Tract Epithelial Cells: In Vitro Models for Human.精液与女性生殖道上皮细胞的相互作用:人类体外模型
Methods Mol Biol. 2025;2897:663-673. doi: 10.1007/978-1-0716-4406-5_45.
2
Post-copulatory genetic matchmaking: HLA-dependent effects of cervical mucus on human sperm function.交配后遗传匹配:宫颈黏液对人类精子功能的 HLA 依赖性影响。
Proc Biol Sci. 2020 Aug 26;287(1933):20201682. doi: 10.1098/rspb.2020.1682. Epub 2020 Aug 19.
3
Purinergic signalling in the reproductive system in health and disease.
健康与疾病状态下生殖系统中的嘌呤能信号传导
Purinergic Signal. 2014 Mar;10(1):157-87. doi: 10.1007/s11302-013-9399-7. Epub 2013 Nov 23.
4
No evidence for killer sperm or other selective interactions between human spermatozoa in ejaculates of different males in vitro.体外实验中,未发现不同男性精液中的人类精子存在杀手精子或其他选择性相互作用的证据。
Proc Biol Sci. 1999 Dec 7;266(1436):2343-50. doi: 10.1098/rspb.1999.0929.
5
Scanning electron-microscopic study of sperm retention and migration in the vagino-cervical region of the rabbit.兔阴道-宫颈区域精子滞留与迁移的扫描电子显微镜研究
Cell Tissue Res. 1982;227(2):387-99. doi: 10.1007/BF00210893.