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[肾上腺素能受体阻断前后骨骼肌的电容性血管反应]

[Capacitive vascular reactions of the skeletal musculature before and after adrenoreceptor blockade].

作者信息

Tkachenko B I, Kudriashov Iu A, Ovsiannikov V I

出版信息

Fiziol Zh SSSR Im I M Sechenova. 1980 Feb;66(2):181-8.

PMID:7364118
Abstract

In acute experiments on cats under autoperfusion of the denervated shank vessels with a constant blood volume, injection of noradrenaline into the perfusate could either decrease or increase vascular capacitance. The character and magnitude of reaction depended on the initial level of venous pressure: in pressure 10--15 Hg the decrease was predominant, whereas in pressure 0 and 25 mm Hg--the increase of vascular capacitance occurred. Under blockade of beta-adrenoreceptors with propranolol the dependence of the character of changes in shank vessels capacitance remained the same. Under dihydroergotoxin blockade of alpha-adrenoreceptors, noradrenaline produced only an insignificant increase of the vascular capacitance.

摘要

在对猫进行的急性实验中,在去神经支配的小腿血管以恒定血容量进行自身灌注的情况下,向灌注液中注射去甲肾上腺素可使血管容量减少或增加。反应的性质和程度取决于静脉压的初始水平:在静脉压为10 - 15 mmHg时,血管容量减少为主,而在静脉压为0和25 mmHg时,血管容量增加。用普萘洛尔阻断β - 肾上腺素能受体后,小腿血管容量变化性质的依赖性保持不变。用二氢麦角毒素阻断α - 肾上腺素能受体后,去甲肾上腺素仅使血管容量有微不足道的增加。

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