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天冬氨酸钾盐和镁盐对小鼠造血及辐射损伤恢复的影响。

Effect of K and Mg salts of aspartic acid on haemopoiesis and recovery from radiation damage in mice.

作者信息

Pospísil M, Netíková J, Pipalová I, Mikeska J

出版信息

Folia Biol (Praha). 1980;26(1):53-61.

PMID:7364133
Abstract

Male mice of a non-inbred strain "H" were used to verify the effect of a 10-day peroral administration of K and Mg aspartates on haemopoietic functions. The salts were proved to stimulate the proliferation and differentiation processes in the thymus, bone marrow and spleen tissues. Mice exposed to a single whole-body X-irradiation after pretreatment with K, Mg aspartate exhibited a more conspicuous postirradiation regeneration of haemopoietic organs and an increased postirradiation survival. The results suggest the possibility of using K, Mg aspartate for radioprotective purposes.

摘要

采用非近交系“H”雄性小鼠来验证连续10天口服天冬氨酸钾和镁对造血功能的影响。已证实这些盐类可刺激胸腺、骨髓和脾脏组织中的增殖和分化过程。在用天冬氨酸钾和镁预处理后接受单次全身X线照射的小鼠,其造血器官在照射后的再生更为明显,照射后的存活率也有所提高。结果表明天冬氨酸钾和镁有可能用于辐射防护目的。

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