Pospísil M, Netíková J, Pipalová I, Mikeska J, Vasků J, Urbánek E
Strahlentherapie. 1979 Aug;155(8):574-8.
The possibility of radioprotective action of K and Mg aspartate administered in tap water for ten days prior to X-irradiation was investigated in male mice of the strain C 57 Bl/10. In normal animals, thymus weight was found to be increased by 10-day treatment with K and Mg aspartate. The postirradiation regeneration of spleen weight and incorporation of radioactive iron into the spleen and femoral marrow following sublethal irradiation was favorably modified by the treatment used. Pretreatment of mice with K and Mg aspartate delays the onset of early deaths at irradiation with an absolutely lethal X-ray exposure and raises the percentage of surviving animals after nearly lethal exposures.
在C 57 Bl/10品系的雄性小鼠中，研究了在X射线照射前10天通过自来水给予天冬氨酸钾和镁的辐射防护作用的可能性。在正常动物中，发现经天冬氨酸钾和镁处理10天可使胸腺重量增加。所采用的处理对亚致死剂量照射后脾脏重量的辐射后再生以及放射性铁掺入脾脏和股骨骨髓的情况有良好的改善作用。用天冬氨酸钾和镁对小鼠进行预处理，可延迟绝对致死剂量X射线照射时早期死亡的发生，并提高近致死剂量照射后存活动物的百分比。
