Ortonne J P, Sannwald C, Thivolet J
Ann Dermatol Venereol. 1978 Jun-Jul;105(6-7):617-24.
33 patients with vitiligo were treated with total body artificial U.V.A. irradiations and systemic 8-MOP. Hexagonal upstanding light boxes containing 84 fluorescent bulbs were used as sources of U.V.A. Patients were treated for 2 months. Response to psoralen photochemotherapy was evaluated as follows: --excellent: greater than 90 p. 100 repigmentation; --good: 50 p. 100 to 90 p. 100 repigmentation; --fair: less than 50 p. 100 repigmentation; --no repigmentation. Excellent results were obtained in 5 patients (15 p. 100), good results in 9 patients (27 p. 100). 6 of the patients (18 p. 100) showed no response. There was no correlation between: --the age of the patients, --the extent of involvement, --the duration of vitiligo and response to therapy. Artificial U.V.A. sources and systemically administrated 8-MOP is at least as effective as 8-MOP + sunlight exposure.
33例白癜风患者接受全身人工紫外线A照射及系统性8-甲氧基补骨脂素治疗。使用装有84个荧光灯泡的六边形立式灯箱作为紫外线A光源。患者接受治疗2个月。对补骨脂素光化学疗法的反应评估如下:——优:色素再生超过90%;——良:色素再生50%至90%;——中:色素再生少于50%;——无色素再生。5例患者(15%)取得优效,9例患者(27%)取得良效。6例患者(18%)无反应。患者的年龄、受累程度、白癜风病程与治疗反应之间无相关性。人工紫外线A光源及系统性给予8-甲氧基补骨脂素至少与8-甲氧基补骨脂素+阳光照射同样有效。