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补骨脂素治疗白癜风效果的比较分析研究(70例患者的研究结果)(作者译)

[Comparative analytical study of the effects of psoralens in vitiligo (findings in 70 patients) (author's transl)].

作者信息

Bouattour H, Chaabouni M

出版信息

Ann Dermatol Venereol. 1978 May;105(5):507-10.

PMID:707943
Abstract

70 patients with vitiligo were divided into two groups. --one group of 40 patients: treated with trioxsalen and sun rays; --one group of 30 patients: treated with methoxsalen and sun rays. Both the first and the second drug stopped the extension almost similarity (87.5 p. 100 positive results for the first group and 86.6 p. 100 for the second one). For the first group the action on the repigmentation was more important but the latent period was longer. Neither group showed side effects worth mentioning. The factors that influence favourably vitiligo and improve the evolution are: --the situation on uncovered parts of the body; --the length of treatment; --the promptness of institution of treatment; --the necessity of a maintenance treatment; --the appearance of erythema which is necessary for repigmentation.

摘要

70例白癜风患者被分为两组。——一组40例患者:用三甲沙林和阳光治疗;——一组30例患者:用甲氧沙林和阳光治疗。两种药物在阻止病情进展方面几乎相似(第一组100例中有87.5例阳性结果,第二组100例中有86.6例)。对于第一组,对色素再生的作用更显著,但潜伏期更长。两组均未出现值得一提的副作用。对白癜风有积极影响并改善病情发展的因素有:——身体暴露部位的情况;——治疗时长;——开始治疗的及时性;——维持治疗的必要性;——色素再生所必需的红斑出现情况。

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