Stengel P W, Frazer D G, Weber K C
J Appl Physiol Respir Environ Exerc Physiol. 1980 Feb;48(2):370-5. doi: 10.1152/jappl.1980.48.2.370.
This study compares the effectiveness of the oxygen absorption and vacuum degassing methods for removing trapped gas from lungs. In addition, the effects of changing vacuum pressure, number of times to degas, and lung orientation during the vacuum degassing procedure were evaluated. To evaluate the two methods, a capacitance spirometer was designed and constructed to record lung volume as lungs were vacuum degassed. When lungs containing trapped gas were degassed in a vacuum chamber, they initially expanded, then slightly decreased in volume until the vacuum was released. Lung volume rapidly decreased as the pressure in the vacuum chamber returned to ambient pressure. The results showed that oxygen absorption atelectasis was more effective in removing gas from the lungs than vacuum degassing the lungs. When vacuum degassing was use, it was found to be most effective when the pressure in the chamber was reduced to the vaporization pressure of H2O and when the lungs were degassed twice. Degassing the lungs more than twice did not significantly remove more gas from the lungs. Lung orientation did not affect the removal of gas during vacuum degassing.
本研究比较了吸氧法和真空脱气法从肺中去除滞留气体的效果。此外，还评估了在真空脱气过程中改变真空压力、脱气次数和肺的方位的影响。为了评估这两种方法，设计并制造了一种电容式肺活量计，用于在肺进行真空脱气时记录肺容积。当含有滞留气体的肺在真空室中脱气时，它们最初会膨胀，然后体积略有减小，直到真空释放。随着真空室中的压力恢复到环境压力，肺容积迅速减小。结果表明，吸氧性肺不张在从肺中去除气体方面比肺的真空脱气更有效。当使用真空脱气时，发现当腔室内压力降至H2O的汽化压力且肺脱气两次时最为有效。对肺脱气超过两次并不能显著地从肺中去除更多气体。肺的方位在真空脱气过程中不影响气体的去除。
