Interventional Pulmonology, Division of Pulmonary and Critical Care Medicine, Henry Ford Hospital, K-17, 2799 W Grand Blvd, Detroit, MI, 48202, USA.
Department of Medicine, Wayne State University, Detroit, MI, USA.
BMC Pulm Med. 2021 Nov 9;21(1):358. doi: 10.1186/s12890-021-01734-w.
Whole Lung Lavage (WLL) has been an important part in the management of Pulmonary Alveolar Proteinosis (PAP) since it improves radiologic and clinical parameters. Bilateral WLL is usually performed in two sessions on different days. Few case reports have described one-session bilateral sequential lung lavage (OSBSWLL), and none have described ambulatory management (same-day discharge).
Demographic characteristics, physiologic parameters, procedure details and outcomes were retrospectively collected on consecutive patients who underwent OSBSWLL for PAP following an ambulatory protocol stablished in our institution.
A total of 13 patients underwent 30 OSBSWLL (61.5% male; mean age 40). The mean SpO2 was 90% (IQR 9) and 94% (IQR 6), before and after OSBSWLL respectively. In 63.3% of cases, patients were discharged home the same day of procedure. Only in two cases (6.6%), patients required post-procedure prolonged mechanical ventilation (> 4 h) due to persistent hypoxia.
OSBSWLL can be performed with same-day discharge.
全肺灌洗（WLL）一直是肺泡蛋白沉积症（PAP）治疗的重要组成部分，因为它可以改善影像学和临床参数。双侧 WLL 通常在不同的两天进行两次。少数病例报告描述了单期双侧序贯肺灌洗（OSBSWLL），并且没有描述门诊管理（当天出院）。
回顾性收集了按照我们机构建立的门诊方案接受 OSBSWLL 治疗 PAP 的连续患者的人口统计学特征、生理参数、程序细节和结果。
共有 13 名患者接受了 30 次 OSBSWLL（61.5%为男性；平均年龄 40 岁）。OSBSWLL 前后的平均 SpO2 分别为 90%（IQR 9）和 94%（IQR 6）。在 63.3%的情况下，患者在当天的手术结束后出院回家。仅在 2 例（6.6%）患者中，由于持续缺氧，患者需要术后延长机械通气（>4 小时）。
OSBSWLL 可以在当天出院时进行。
