Webb P J, Wright K W, Winter G D
J Bone Joint Surg Br. 1980 May;62-B(2):174-9. doi: 10.1302/0301-620X.62B2.7364830.
This paper presents a prospective trial carried out using the Monk "soft top" endoprosthesis in 33 patients. Two years after operation 70 per cent of the remaining patients had pain. A biomechanical and histopathological analysis of the endoprosthesis and the surrounding tissue, obtained from a further two patients at the time of revision, is presented. It is concluded that the prosthesis has inherent design faults which result in excessive wear of the polyethylene component. The wear debris produced stimulates a prolific fibrous tissue reaction which is associated with progressive clinical deterioration.
本文介绍了一项对33例患者使用Monk“软顶”内置假体进行的前瞻性试验。术后两年，其余患者中有70%出现疼痛。本文还展示了从另外两名患者翻修时获取的内置假体及周围组织的生物力学和组织病理学分析结果。得出的结论是，该假体存在固有设计缺陷，导致聚乙烯部件过度磨损。产生的磨损碎片刺激了大量纤维组织反应，这与临床病情的逐渐恶化有关。
